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Vaccination: Varicella-Zoster Virus Vaccine

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Total 337 results found since Jan 2013.

A quick algorithmic review on management of viral infectious diseases in pediatric solid organ transplant recipients
Front Pediatr. 2023 Sep 4;11:1252495. doi: 10.3389/fped.2023.1252495. eCollection 2023.ABSTRACTPediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients are at an increased risk of viral infections due to their immunosuppressed state. The most commonly encountered viruses include cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV), varicella-zoster virus (VZV), ad...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Marjan Moghadamnia Hamid Eshaghi Hosein Alimadadi Simin Dashti-Khavidaki Source Type: research

Varicella vaccine meningoencephalitis in a child receiving autologous bone marrow transplantation
CONCLUSIONS: Our experience highlights the importance of conducting a thorough medical history regarding vaccination and serological status of newly immunocompromised patients. Intensive chemotherapy succeeding live vaccine administration <4 weeks could have influenced early and severe viral reactivation. Early initiation of prophylactic antiviral treatment is questioned in such circumstances.PMID:37395442 | DOI:10.1111/petr.14562
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Raad Coralie Chebel Ziad Renaud Christian Teira Pierre Buteau Chantal Tapi éro Bruce Ovetchkine Philippe Source Type: research

Disseminated vaccine-induced varicella infection in a kidney transplant recipient
Am J Transplant. 2023 Jun 5:S1600-6135(23)00522-1. doi: 10.1016/j.ajt.2023.05.034. Online ahead of print.ABSTRACTA 33-year-old kidney transplant (KT) recipient presented with a disseminated pruritic, painful, vesicular rash and hepatitis three weeks after receiving a varicella vaccine (VAR). A skin lesion biopsy sent to the Centers for Disease Control and Prevention (CDC) for genotyping confirmed vaccine-strain varicella-zoster virus (VZV) (Oka strain; vOka). The patient was successfully treated with intravenous acyclovir during a prolonged hospital stay. This case supports the contraindication of VAR in adult KT recipient...
Source: Herpes - June 7, 2023 Category: Infectious Diseases Authors: Megan A Berman Richard E Rupp Source Type: research

Public health impact of recombinant zoster vaccine for prevention of herpes zoster in US adults immunocompromised due to cancer
This study evaluates the public health impact of recombinant zoster vaccine (RZV) relative to no HZ vaccination for the prevention of HZ among adults aged ≥18 years diagnosed with selected cancers in the United States (US). A static Markov model was used to simulate three cohorts of individuals who are IC with cancer (time horizon of 30 years; one-year cycle length): hematopoietic stem cell transplant (HSCT) recipients, patients with breast cancer (BC; a solid tumor example), and patients with Hodgkin's lymphoma (HL; a hematological malignancy example). Cohort sizes reflect the estimated annual incidence of each conditio...
Source: Herpes - March 7, 2023 Category: Infectious Diseases Authors: Desmond Curran Brandon J Patterson Justin Carrico Ahmed Salem Elizabeth M La St éphane Lorenc Katherine A Hicks Sara Poston Christopher F Carpenter Source Type: research

Clinical effectiveness of zoster vaccine live in kidney transplant recipients immunized prior to transplantation: a retrospective single-center cohort study
CONCLUSIONS: Our study, the first on the clinical effectiveness of zoster vaccines for KT recipients, suggests that ZVL before transplantation effectively prevents HZ.PMID:36868356 | DOI:10.1016/j.cmi.2023.02.014
Source: Herpes - March 3, 2023 Category: Infectious Diseases Authors: Si-Ho Kim Kyungmin Huh Kyo Won Lee Jae Berm Park Woo Seong Huh Jae-Hoon Ko Sun Young Cho Cheol-In Kang Doo Ryeon Chung Kyong Ran Peck Source Type: research

Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed. The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Patterns of use of recombinant zoster vaccine among commercially-insured immunocompetent and immunocompromised adults 50-64  years old in the United States
CONCLUSIONS: RZV uptake was low in the two years since the CDC recommendation, and differed by demographic, healthcare access, and clinical characteristics. Initiation rates were higher among immunocompromised adults compared to immunocompetent adults, despite no CDC recommendation for vaccination in these groups during the study period. The CDC has since recommended RZV for immunocompromised individuals, and our findings may inform efforts to increase RZV uptake in individuals at higher risk of severe disease.PMID:36396511 | DOI:10.1016/j.vaccine.2022.10.076
Source: Herpes - November 17, 2022 Category: Infectious Diseases Authors: Jonathan Fix Nadja A Vielot Jennifer L Lund David J Weber Jennifer S Smith Michael G Hudgens Sylvia Becker-Dreps Source Type: research

Seroprevalence of VZV IgG antibody in kidney transplant recipients: A systematic and meta-analysis review
CONCLUSION: In this study, our results demonstrated that VZV is a prevalent infectious agent in kidney transplant recipients. A prophylactic vaccine may provide an effective strategy for preventing VZV in renal transplant recipients and also provide prophylaxis against the occurrence of post-herpetic neuralgia in immunocompetent patients.PMID:36341911 | DOI:10.1016/j.trim.2022.101730
Source: Transplant Immunology - November 7, 2022 Category: Transplant Surgery Authors: Mina Alimohammadi Mahmood Moosazadeh Alireza Mardomi Tahoora Mousavi Source Type: research

Natural History of Herpes Zoster in the Placebo Groups of Three Randomized Phase  III Clinical Trials
CONCLUSION: The incidence and burden of HZ is high in immunocompetent adults aged ≥ 50 YOA and even more so in HSCT recipients aged ≥ 18 YOA.PMID:36322332 | DOI:10.1007/s40121-022-00689-7
Source: Herpes - November 2, 2022 Category: Infectious Diseases Authors: Desmond Curran Sean Matthews C éline Boutry Nicolas Lecrenier Anthony L Cunningham Kenneth Schmader Source Type: research